The Big Bang Theory

Season 1 Episode 4:

The Luminous Fish Effect

Sheldon's getting fired forces him to explore what life has to offer outside physics, leaving Leonard to take drastic action to snap his friend out of his funk.
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About The Big Bang Theory:

The Big Bang Theory is centered on five characters living in Pasadena, California: roommates Leonard Hofstadter and Sheldon Cooper; Penny, a waitress and aspiring actress who lives across the hall; and Leonard and Sheldon's equally geeky and socially awkward friends and co-workers, mechanical engineer Howard Wolowitz and astrophysicist Raj Koothrappali. The geekiness and intellect of the four guys is contrasted for comic effect with Penny's social skills and common sense.