South Park

Season 12 Episode 11:

Pandemic 2: The Startling

Craig and the boys are stranded in the Andes Mountains while giant guinea pigs wreak havoc all over the planet. Craig is the only person who can end the terror, but he doesn't care and won't do anything about it.
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About South Park:

Follows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.