South Park

Season 12 Episode 10:

Pandemic

With Craig's help, the boys start up a Peruvian pan flute band to make money. However, they are detained by Homeland Security and sent to Peru to end the 'Pandemic.' In the pan flute bands' absence, giant guinea pigs invade South Park.
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About South Park:

Follows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.